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Abbrevia: S. P. J. App Bio Res.


Language: English


ISSN: 2315-6287


DOI: 10.14412/SPJABR


 S. P. J. App Bio Res.

3(1):009-018, August 2019

View: PDF (216KB) 



Science Park Journal of Applied Biotechnology Research, 3(1), pp 009-018, August 2019


(ISSN 2315-6287) 2019 Science Park Journals



Full Length Research Paper


Method for the Study of Nonlinear Kinetics of Coil - Helix Transition for Collagen-Type Peptides and Prospects for its Use in the State-of-the Art Medical Technologies.


Liena Yu. Vergun (1) , Valeri E. Oriol(2) , Olga A. Zagorodnia (1)


(1) Taras Shevchenko Kyiv National University, Physical Department, Ukraine

(2) National Institute of Cancer, Kyiv, Ukraine




Abstract: A method for study of nonlinear kinetics of coil-helix transition in collagen-type structures has been proposed. The method has been tested for one of such structures with molecules having 40 nm in length. On the basis of experimental data a time of shaping of triple helix has been estimated. The given method has been proposed to be used in selecting a length of СМР (Collagen Mimetic Peptides) molecules used in the modern medical science.


Keywords: kinetics of coil-helix transition, collagen-type structures, molecular light dispersion


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